Praxis replaces Epic's fragmented specialty landscape — Beacon for oncology, Stork for OB, and disconnected workflows for transplant, rehabilitation, and home health — with a unified specialty clinical platform. Each discipline retains its unique clinical workflows, documentation patterns, and regulatory requirements. But all five share a single patient record, a single ordering engine, a single Sentinel AI layer, and a single analytics framework. The specialty is the context. Clarion is the foundation.
Epic addresses specialty medicine through dedicated modules — Beacon for oncology, Stork for obstetrics, Bones for orthopedics, Cupid for cardiology — each built as a separate application within the Epic ecosystem. The modules share a database, but they impose different workflows, different documentation paradigms, and different user experiences on clinicians who must navigate between them. A patient with breast cancer who becomes pregnant does not fit neatly into Beacon or Stork. A transplant patient who develops cancer is managed in two systems with two treatment plans that do not speak to each other. The fragmentation mirrors Epic's development history, not the patient's clinical reality.
Praxis takes the opposite approach: one platform with specialty-aware workflows that adapt to the clinical domain without fragmenting the patient record.
Each module below is a complete specialty practice management system with its own clinical workflows, documentation templates, ordering protocols, and regulatory reporting. But all eight share a single patient record, a single clinical data model, and a single integration layer through Clarion Conduit. The patient is never fragmented, even when their care spans multiple specialties.
Oncology is the most protocol-driven specialty in medicine. Every chemotherapy regimen is a precisely calibrated sequence of drugs, doses, intervals, and response assessments that varies by cancer type, stage, molecular markers, and patient tolerance. Praxis manages the entire oncology lifecycle: treatment plan creation from NCCN-guideline-mapped protocols, dose calculation based on body surface area with automatic renal and hepatic adjustments, cumulative toxicity tracking across cycles, infusion scheduling through Clarion Tempo, chemotherapy order verification through Clarion Apotheca, and radiation therapy dose tracking integrated with the radiation oncology treatment planning system. Tumor staging follows AJCC 8th Edition with automated submission to the National Cancer Database. Molecular biomarker results from Clarion Assay inform precision therapy selection — HER2 status, PD-L1 expression, microsatellite instability, and genomic profiling from next-generation sequencing.
Obstetrics is unique in medicine: two patients occupy one body, the clinical timeline spans 40 weeks of longitudinal care punctuated by the most acute event in the entire episode, and the liability profile is the highest of any specialty. Praxis manages the complete pregnancy episode from first prenatal visit through delivery and postpartum follow-up. The prenatal module tracks gestational age, growth curves, lab results mapped to trimester-specific reference ranges, genetic screening results, and risk factors that flag the pregnancy as high-risk for maternal-fetal medicine referral. The labor and delivery module integrates with electronic fetal monitoring systems to capture and trend fetal heart rate patterns in the clinical record, documents cervical change with partogram visualization, and supports structured documentation for cesarean delivery, vacuum extraction, and operative vaginal delivery. The newborn transition is seamless — the infant's record is auto-created from the maternal record with Apgar scoring, birth weight, gestational age, and initial assessments pre-populated.
Transplant medicine operates on a timeline measured in decades, not visits. A kidney transplant recipient will take immunosuppressive medications, undergo surveillance labs, and be monitored for rejection, infection, and malignancy for the rest of their life. Praxis manages this longitudinal journey from pre-transplant evaluation through waitlist management, perioperative care, and lifetime post-transplant surveillance. The pre-transplant module coordinates the multi-disciplinary evaluation workup — cardiology clearance, pulmonary function testing, psychosocial assessment, financial counseling — tracking each element's completion status. UNOS waitlist integration manages the listing, status changes, and organ offer documentation. Post-transplant protocols enforce immunosuppression monitoring with drug level tracking through Clarion Assay, calculated trough levels correlated with graft function trends, and Sentinel AI detection of early rejection signals from biopsy pathology, donor-specific antibody levels, and creatinine trajectory.
Rehabilitation medicine measures progress in functional units that the rest of the EHR ignores — FIM scores, range of motion, grip strength, gait velocity, swallowing function, cognitive assessment scales. Epic provides no dedicated rehab module; rehabilitation documentation is forced into general ambulatory or inpatient charting templates that are not designed for the discipline. Praxis includes a purpose-built rehabilitation module supporting inpatient rehabilitation facilities (IRF), outpatient physical therapy, occupational therapy, and speech-language pathology. Therapists document functional assessments using validated instruments (FIM, AM-PAC, DASH, PHQ-9) with longitudinal trend tracking that visualizes patient progress across the rehabilitation episode. The IRF-PAI (Patient Assessment Instrument) for CMS compliance is auto-populated from clinical documentation. Treatment plans are goal-oriented with measurable functional targets, and progress toward those targets is tracked graphically for both the care team and the patient.
Home health is the only care setting where the clinician goes to the patient. This imposes unique requirements: mobile-first documentation that works on a tablet in a patient's living room, offline capability for visits in areas without reliable connectivity, and structured assessment instruments (OASIS-E2 for CMS compliance) that must be completed accurately to determine reimbursement. Praxis provides a home health module with a mobile-first interface designed for visiting nurses, physical therapists, occupational therapists, speech therapists, medical social workers, and home health aides. The OASIS assessment is integrated into the clinical workflow so that completing the clinical visit simultaneously generates the regulatory documentation required for payment. Visit scheduling, routing optimization based on geography and patient acuity, and care plan management are coordinated through Clarion Tempo. Data captured during home visits synchronizes to the central clinical record when connectivity is restored, ensuring that the acute care team sees the same patient record as the home health team.
Clinical trials are the bridge between current practice and future cures — yet fewer than 5% of eligible cancer patients are enrolled in trials, largely because trial identification is a manual, time-intensive process that occurs after the treatment decision has already been made. Praxis integrates clinical trial screening directly into the specialty workflow. When an oncologist documents a new cancer diagnosis with stage, histology, and molecular markers, the system automatically screens the patient against active trial protocols at the institution and across the national trial network. Matching trials are presented to the physician with eligibility criteria, inclusion and exclusion status, and a one-click referral to the research coordinator. Trial-enrolled patients have their study visits, protocol-required labs, and adverse event documentation tracked within the same clinical record, eliminating the dual-documentation burden that frustrates both clinicians and research coordinators.
Specialty medications — biologics, immunotherapies, targeted therapies, gene therapies — represent the fastest-growing pharmacy cost category and the most complex prescribing workflow. A single immunotherapy order can require prior authorization from the payer, enrollment in a REMS program, coordination with a specialty pharmacy for distribution, clinical monitoring for immune-related adverse events, and ongoing labs to determine treatment continuation. Praxis integrates specialty pharmacy workflows directly into the clinical module for each relevant specialty. When an oncologist orders pembrolizumab, the system simultaneously initiates prior authorization through Clarion Arbiter RCM, verifies REMS enrollment status, checks thyroid and hepatic function for baseline safety monitoring, and schedules the infusion through Clarion Tempo. The clinician places one order. The system orchestrates six parallel workflows.
Every specialty in Praxis generates data that feeds national registries, quality programs, and research databases. Cancer registrars submit to the National Cancer Database and state registries. Obstetrics departments report to the National Perinatal Information Center. Transplant programs submit outcomes to UNOS/SRTR. Rehabilitation facilities report IRF-PAI data to CMS. Home health agencies submit OASIS data for reimbursement and quality scoring. In legacy systems, this registry reporting requires dedicated abstractors who manually review charts and enter data into separate submission systems. In Praxis, registry data is captured from clinical documentation as care is delivered, validated against completeness requirements in real time, and submitted electronically to the appropriate registry without manual abstraction. Specialty-specific quality dashboards track measures relevant to each discipline — oncology survival rates, cesarean section rates, graft survival, functional independence measure gains, and home health readmission rates — all from a single analytics platform.
A NCI-designated cancer center treating 14,000 new cancer cases annually deployed Praxis to replace Epic Beacon and a standalone clinical trial management system. The automatic trial eligibility screening identified 4,200 patients meeting trial criteria in the first year — a population the research coordinators would have taken months to identify manually. Trial enrollment increased 3.4x, from 4.1% of eligible patients to 14.2%. The AJCC staging and registry submission module eliminated the need for four full-time cancer registrar positions, as staging data was captured from clinical documentation and submitted electronically. Biomarker-guided therapy selection through Clarion Assay integration ensured that 100% of NSCLC patients had PD-L1 testing completed before treatment plan finalization, compared to 72% under the prior workflow.
A health system delivering 8,400 babies per year across four labor and delivery units deployed Praxis to replace Epic Stork and a standalone fetal monitoring archival system. The integrated EFM trending module eliminated the workflow where nurses printed fetal heart rate strips and clipped them to the chart — a process that introduced documentation gaps during emergent deliveries. Fetal heart rate patterns were streamed directly into the clinical record, and the Sentinel Neo engine analyzed tracings for Category II and III patterns, alerting the care team within 90 seconds of a concerning pattern change. Adverse neonatal events decreased 22% in the first year. The postpartum depression screening module achieved 94% screening completion, compared to 68% when screening was a separate paper-based process. Newborn records were auto-created in under 30 seconds from the delivery event, eliminating the manual registration that had previously delayed newborn orders by an average of 12 minutes.
I treat patients with breast cancer. Some of them are pregnant. In our old system, the oncology team worked in Beacon and the OB team worked in Stork. When I needed to know what chemotherapy was safe for a patient in her second trimester, I had to open two systems and correlate the data myself. In Praxis, it is one patient. One record. One treatment plan that accounts for both the cancer and the pregnancy. The first time I opened a patient's chart and saw her gestational age next to her tumor staging, I knew we had built the right system.
Our transplant patients do not stop being transplant patients when they go home. They do not stop when they develop cancer ten years later from immunosuppression. They do not stop when they need rehabilitation after a stroke. Every encounter, in every setting, for the rest of their lives, must be informed by the fact that they have a transplanted organ and take immunosuppressive medications. In the old world, that information lived in a specialty module that no one outside transplant ever opened. In Praxis, it lives in the patient record. Every provider sees it. Every order is checked against it. That is what it means to build a system around the patient instead of around the department.
See Praxis configured for your specialty portfolio, your clinical protocols, and your registry requirements.